United States: COVID-19 has been linked with another major issue for the population suffering from the SARS-CoV-2 virus – the primary reason behind the occurrence of a pandemic. As per the experts and several researchers, approximately 10 to 30 percent of the general population has dealt with some cognitive impairment since the outset of the global pandemic.

According to the reports, the major issues experienced by the people include brain fog, memory loss and trouble in concentration. The researchers have claimed that there is the research was conducted to explore the mechanism behind the phenomenon and also highlighted that the changes are seen because of presence of some protein.

New Research to Reduce the Impact of Memory Loss!

A recently conducted research has outlined that experts have been working to develop a vaccine which can help in reducing the impacts of the memory loss after the COVID-19 infections. The research has been conducted by the health professionals at Western and Washington University School of Medicine in St Louis and has been published in Nature Immunology, according to medicalxpress.com.

The impact of COVID-19 towards cognitive impairment was studied through a rodent model and the research team included Schulich School of Medicine & Dentistry professor Dr Robyn Klein.

While emphasising the research and its finding, research-lead Klein mentioned, “We looked carefully at their brains during acute infection and then later after recovery to discover what was abnormal in terms of the different immune cells trafficking into the brain and their effects on neural cells.” It is to be noted that Klein works as the Canada Excellence Research Chair in Neurovirology and Neuroimmunology.

Klein was worried about reports of cognitive problems during the early days of the pandemic. This raised questions among researchers about whether the virus was affecting the brain. Klein had previously researched viruses that attack the brain, according to medicalxpress.com.

Furthermore, Klein elaborated, “We had previously shown that the virus could not be detected in human or hamster brains, and this study also showed that the virus was not invading the central nervous system.” He also emphasized that the study’s findings highlighted that cognitive impairment is due to some other mechanism.

The experts pinpointed that SARS-CoV-2 infection augments concentrations of brain Interleukin-1 beta (IL-1β), a cytokine protein influential on the immune system. They discerned that subjects with heightened IL-1β levels experienced a decline in neurogenesis—the genesis of new neurons in the cerebrum—and exhibited memory deterioration.

The team inferred that IL-1β might be a pivotal mechanism behind SARS-CoV-2-induced cognitive decline, speculating whether prophylactic vaccination could avert this.

Subsequently, researchers scrutinized the impact on vaccinated subjects. They discerned a promising association between vaccination and diminished cognitive impairments, such as memory decline, as per reports by medicalxpress.com.

The inquiry revealed that antecedent vaccination mitigated cerebral inflammation and decreased IL-1β levels. Consequently, the vaccinated subjects encountered a reduced detriment to memory and cerebral function.

Klein asserted that additional investigation is requisite to comprehensively elucidate how vaccinations are effectuating this outcome and to determine if it is applicable to humans.

Klein, while explaining the same, was quoted saying, “We know there’s anecdotal evidence that humans who’ve been vaccinated have a much lower risk of developing this long COVID brain fog.”

Moreover, Klein clarified that vaccine in the research is not same to the available vaccine for the general public. He then pointed out that more study and in-depth research is required to conclude the relation between COVID-19 and cognitive impacts and vaccination.

Klein stated, “What we do know is that if you’re vaccinated, you have much less inflammation,” according to medicalxpress.com.

She further mentioned that vaccination will only decrease the risk of the impacts of infection but will not completely prevent it. The expert outlined, “People need to understand that about vaccines. They need to know what vaccines can do and what they can’t do.”

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